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[Update on the treatment of hereditary angioedema in Argentina]

Blas Larrauri1,2, Alejandro Malbrán2, Eloisa Malbrán2

  • 1Unidad de Alergia, Asma e Inmunología Clínica, San Juan, Argentina.

Medicina
|April 8, 2025
PubMed

Hereditary angioedema (HAE) is a rare autosomal dominant disease, characterized by episodes of edema involving the skin, gastrointestinal tract and larynx. HAE has a 15% to 50% historical asphyxia mortality. It is the consequence of C1 inhibitor deficiency. The identification of bradykinin as the principal mediator of the disease has led to the development of new drugs for the treatment of HAE. HAE treatment is agreed in international consensus. A therapeutic guide for the treatment of the disease was published in Medicina (Buenos Aires) in 2012, but new and relevant diagnostic and therapeutic advances have been described subsequently. We here update the pharmacology of new drugs available for the treatment of HAE in Argentina, as well as briefly describe the new forms of the disease.

Keywords:
C1 inhibitorhereditary angioedematreatment

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