MR imaging in adrenoleukomyeloneuropathy

A 54-year-old patient with clinical and biochemical features of the adrenoleukomyeloneuropathy-complex is reported. Although CT was essentially normal, magnetic resonance (MR) showed areas of prolonged T1 and T2 values in the corpus callosum, around the trigones of the lateral ventricles, in the internal capsules, in the pons, and in the cervical spinal cord. This case report indicates that MR is better suited than CT to detect demyelination of the cerebral white matter and of descending tracts.