Related Experiment Video

Updated: May 20, 2025

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

85.7K

Increased incidence of complicated appendicitis in patients with neurodevelopmental disabilities

Daniela Feingold1, Nupur Shridhar2, Jianyou Liu2

  • 1Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA; Jacobi Medical Center, 1400 Pelham Parkway South, Bronx, NY, 10461, USA.

American Journal of Surgery
|April 8, 2025
PubMed

Insights

Patients with neurodevelopmental disabilities (NDD) are more likely to experience complicated appendicitis. This study highlights potential healthcare disparities in emergency general surgery for individuals with disabilities.

Area of Science:

  • Surgery
  • Public Health
  • Health Disparities

Background:

  • Healthcare disparities for patients with disabilities in surgery are understudied.
  • Understanding these disparities is crucial for improving surgical care.
  • Patients with disabilities may face unique challenges in accessing timely and effective treatment.

Purpose of the Study:

  • To investigate if patients with neurodevelopmental disabilities (NDD) present with more complicated appendicitis than those without.
  • To identify potential disparities in emergency general surgery outcomes for patients with NDD.

Main Methods:

  • Retrospective review of acute appendicitis cases (2016-2021) in a large US public hospital system.
  • Inclusion of patients under 50 years old.
  • Identification of NDD patients using ICD-10 codes and matching to controls (1:2 ratio) by age, gender, and race/ethnicity.

Main Results:

  • Patients with NDD had a significantly higher incidence of complicated appendicitis (OR 2.15, p=0.003).
  • NDD patients experienced longer lengths of stay (LOS).
  • Increased rates of post-operative complications were observed in the NDD group.

Conclusions:

  • Patients with neurodevelopmental disabilities face a higher risk of complicated appendicitis.
  • Findings suggest a potential healthcare disparity in emergency general surgery for patients with disabilities.
  • Further research is needed to address and mitigate these disparities.

Keywords:
Acute care surgeryDisabilityDisparitiesEmergency general surgerySurgery

More Related Videos

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

11.3K
A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy10:02

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy

Published on: November 3, 2016

24.0K

Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
73
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
54
Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
52
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
141
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
103
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
34