Evaluation of the presence of sarcopenia and the relationship with disease activity in fibromyalgia
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View abstract on PubMed
Summary
This summary is machine-generated.Sarcopenia, a muscle-wasting condition, is common in fibromyalgia syndrome (FMS) patients. Early detection and evaluation of sarcopenia may improve FMS treatment outcomes.
Area Of Science
- Rheumatology
- Gerontology
- Muscle Physiology
Background
- Fibromyalgia syndrome (FMS) is a chronic condition characterized by widespread pain and fatigue.
- Sarcopenia, age-related muscle loss, can impact physical function and quality of life.
- The prevalence and impact of sarcopenia in FMS patients remain underexplored.
Purpose Of The Study
- To investigate the presence of sarcopenia in female fibromyalgia patients.
- To examine the relationship between sarcopenia, physical performance, disease activity, and pain in FMS.
- To compare sarcopenia indicators between FMS patients and healthy controls.
Main Methods
- Fifty female FMS patients and 50 healthy controls were enrolled.
- Sarcopenia screening utilized the SARC-F questionnaire and ISarcoPRM criteria.
- Disease activity and pain were assessed using the Fibromyalgia Impact Questionnaire (FIQ) and Numerical Rating Scale.
- Muscle strength (grip) and thickness (quadriceps femoris) were measured.
Main Results
- Sarcopenia was diagnosed in 40% of FMS patients versus 12% of controls (p < 0.001).
- FMS patients exhibited significantly lower hand grip strength (p = 0.007) but similar thigh muscle thickness (p = 0.875).
- Higher SARC-F scores correlated positively with disease activity (FIQ) in FMS patients with sarcopenia (r = 0.708, p < 0.001).
Conclusions
- Sarcopenia is a prevalent condition among individuals with fibromyalgia syndrome.
- Assessing sarcopenia in FMS patients is crucial for potentially enhancing treatment efficacy.
- These findings highlight the need to consider muscle health in FMS management.
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