Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Physiologic changes during a marathon, with special reference to magnesium.

K B Franz, H Rüddel, G L Todd

    Journal of the American College of Nutrition
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Sepsis: case numbers increasing worldwide but new strategies too].

    Der Anaesthesist·2016
    Same author

    [Validation of an advance directive].

    Der Anaesthesist·2010
    Same author

    [New pain diagnosis in the German version of the ICD-10].

    Der Nervenarzt·2008
    Same author

    Tsg101 is upregulated in a subset of invasive human breast cancers and its targeted overexpression in transgenic mice reveals weak oncogenic properties for mammary cancer initiation.

    Oncogene·2007
    Same author

    Dietary magnesium deficiency decreases plasma melatonin in rats.

    Magnesium research·2006
    Same author

    Influence of graded magnesium deficiencies on white blood cell counts and lymphocyte subpopulations in rats.

    Magnesium research·2006

    This case study reveals significant physiological shifts during a marathon, including substantial increases in stress hormones and white blood cells. Some hormone levels and serum magnesium remained altered post-race, indicating prolonged physiological impact.

    Area of Science:

    • Exercise Physiology
    • Human Physiology
    • Sports Medicine

    Background:

    • Marathon running induces significant physiological stress.
    • Understanding the dynamic changes in hormones and blood markers during endurance events is crucial for athlete health and performance.
    • Limited data exists on the comprehensive physiological response in a single, moderately trained individual over the course of a marathon.

    Purpose of the Study:

    • To document the serial physiological changes in a healthy, moderately trained male during and after marathon completion.
    • To investigate alterations in catecholamines (epinephrine, norepinephrine, dopamine), cortisol, white blood cells, thromboxane B2, and serum magnesium.
    • To explore potential relationships between these markers, such as thromboxane B2 and serum magnesium.

    Main Methods:

    Related Experiment Videos

    • A single case study design was employed.
    • Blood samples were collected at multiple time points: pre-race, 1 hour, 2 hours, end of race, and 1 hour post-recovery.
    • Analysis included measurements of norepinephrine, epinephrine, dopamine, cortisol, white blood cells, thromboxane B2, and serum magnesium.

    Main Results:

    • Significant elevations in norepinephrine, epinephrine, and dopamine were observed within the first hour, with norepinephrine and dopamine remaining high post-recovery.
    • Cortisol levels doubled by the race's end and stayed elevated.
    • White blood cells increased four-to-five-fold by the end of the race; Thromboxane B2 showed a nine-fold increase, inversely related to serum magnesium, which dropped significantly at the race's conclusion.

    Conclusions:

    • Marathon running triggers profound and sustained neuroendocrine and hematological responses.
    • The observed decrease in serum magnesium at the end of the race may correlate with increased plasma free fatty acids.
    • Further research is needed to elucidate the long-term implications of these marathon-induced physiological changes.