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The Association between Tea Consumption and Bladder Cancer Risk Based on the Bladder Cancer Epidemiology and
Yan-Xi Zhang1,2, Richard Albers3, Ya-Ting Chen1,2
1Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, China.
Nutrition and Cancer
|April 9, 2025
Summary
Drinking herbal tea may reduce bladder cancer risk. Overall tea consumption showed a protective association, with risk decreasing as intake increased. Further research is needed to understand the mechanisms.
Area of Science:
- Epidemiology
- Nutritional Science
- Oncology
Background:
- Inconsistent evidence exists on tea consumption and bladder cancer (BC) risk.
- International data is needed to clarify this association.
Purpose of the Study:
- To investigate the association between tea consumption and bladder cancer risk using pooled international data.
- To explore potential differences in risk reduction across various tea types (black, green, herbal).
Main Methods:
- Pooled individual data from 15 case-control studies (2,347 cases, 6,871 controls).
- Multilevel multivariable logistic regression analysis adjusted for dietary and non-dietary factors.
- Stratified analyses by tea type, gender, and smoking status.
Main Results:
- Overall tea consumption was associated with a reduced BC risk (OR=0.72, 95% CI=0.65-0.80).
- Herbal tea consumption showed a significant inverse association with BC risk (OR=0.59, 95% CI=0.36-0.96).
- No significant association was found for black or green tea; risk decreased with increased daily tea intake (<5.67 cups/day).
Conclusions:
- Herbal tea, but not *Camellia sinensis* (black/green) tea, is inversely linked to bladder cancer incidence.
- While some strata showed significant findings, further research is required to elucidate the underlying biological mechanisms.
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