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[Mineral and trace elements in human urine].

P Schramel, G Lill, S Hasse

    Journal of Clinical Chemistry and Clinical Biochemistry. Zeitschrift Fur Klinische Chemie Und Klinische Biochemie
    |May 1, 1985
    PubMed
    Summary
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    This study establishes reference values for essential mineral and trace elements in human urine. These findings provide crucial data for assessing normal physiological levels and occupational exposure to elements like barium, strontium, and titanium.

    Area of Science:

    • Clinical Chemistry
    • Analytical Chemistry
    • Toxicology

    Context:

    • Establishing reliable reference ranges for mineral and trace elements is vital for clinical diagnostics and occupational health monitoring.
    • Human urine is a key biological matrix for assessing exposure and excretion of various elements.

    Purpose:

    • To determine reference values for a comprehensive panel of mineral and trace elements in healthy adults.
    • To provide data on physiological excretion levels for elements relevant to occupational medicine.
    • To establish baseline data for comparison with potentially exposed populations.

    Summary:

    • Analyzed 24-hour human urine samples from approximately 100 healthy individuals (aged 20-50) for elements including Al, B, Ca, Cu, Fe, K, Li, Mg, Na, P, and Zn using Inductively Coupled Plasma (ICP) and Direct Current Plasma (DCP) emission spectroscopy.

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  • Established mean values and ranges for substance concentrations and 24-hour excretion.
  • Reported physiological reference values for Ba, Sr, and Ti, with examples of workplace exposure increases, and measured average values for Cd, Co, Ni, and Pb using voltammetry.

    • Impact:

    • Provides essential reference data for clinical laboratories and occupational health professionals.
    • Facilitates the accurate assessment of human exposure to environmental and occupational elements.
    • Supports the development of biomonitoring strategies for workplace safety and public health surveillance.