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Predicting sleep disordered breathing in middle-aged Japanese office workers: A simple and effective screening tool
Wakako Yamasawa1, Akiko Tanabe2, Koichiro Asano3
1Department of Laboratory Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan; Clinical Laboratory, Keio University Hospital, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Background:
Sleep Disordered Breathing (SDB) is a common yet underdiagnosed condition, as many afflicted individuals are unaware of the condition. It is a major contributor to metabolic syndrome, sudden death, and deteriorating overall health, making early detection crucial, especially in populations such as Japanese office workers in whom symptoms may not be evident. This study aimed to fill the critical gap in SDB detection by investigating its prevalence among Japanese office workers unaware of any SDB symptoms and by and developing a straightforward, effective screening tool that can be integrated into routine health examinations.
Methods:
A total of 518 male office workers underwent a sleep monitoring test along with a comprehensive questionnaire assessing lifestyle, comorbidities, and sleep quality. Participants were divided into derivation and validation cohorts to develop and test, respectively, an SDB prediction score.
Results:
In this study, 149 (28.7 %) patients had a respiratory disturbance index ≥15 and moderate or severe SDB. The developed prediction model demonstrated a high sensitivity of 91.5 % and a specificity of 49.4 %, making it a powerful tool for early detection of SDB requiring treatment.
Conclusions:
This study presents a convenient screening tool that could revolutionize SDB detection among Japanese office workers, leading to earlier interventions and potentially reducing the burden of related health complications. This tool holds significant promise for incorporation into standard health examinations, offering a proactive approach to managing SDB.
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