Cerebral gumma. Case report.

Area of Science:

• Neurology
• Neuroimaging
• Infectious Diseases

Background:

• Neurosyphilis, a tertiary manifestation of Treponema pallidum infection, can present with diverse neurological symptoms.
• Cerebral gummas are rare but significant lesions that require accurate diagnosis and timely treatment.

Observation:

• A focal cerebral syphilitic gumma was identified in the right temporal lobe.
• Angiography demonstrated moderate focal hypervascularity, vessel stretching, and wall irregularities.
• Computed tomography revealed a low-density area with strong enhancement post-contrast administration.

Findings:

• The imaging findings, including hypervascularity and contrast enhancement, are consistent with a cerebral gumma.
• The combination of angiography and computed tomography provided crucial diagnostic information.

Implications:

• This case highlights the importance of considering neurosyphilis in the differential diagnosis of brain lesions, even in the absence of typical symptoms.
• Accurate neuroimaging interpretation is vital for diagnosing rare syphilitic brain involvement.
• Prompt diagnosis and treatment of cerebral gummas can prevent severe neurological sequelae.