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Pyogenic Vertebral Osteomyelitis
Michael W Henry1, James E Dowdell2, Andy O Miller3
1Department of Internal Medicine, Division of Infectious Diseases, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.
None:
Vertebral osteomyelitis is a general term for a heterogenous group of spine infections involving the vertebral bone, intervertebral discs, and facet joints. These infections can often spread contiguously to adjacent paraspinal structures, including paravertebral muscles and the epidural space and frequently presents with nonspecific and indolent symptoms, which can delay diagnosis. Treatment can be arduous, requiring prolonged courses of antibiotics often combined with surgical debridement. This review focuses primarily on pyogenic vertebral osteomyelitis in adults, reviewing the pathophysiology, epidemiology, microbiology, diagnosis, and treatment of this infection.
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