Enhanced recovery after urological reconstructive surgery in pediatric patients: a systematic review and
Fabiola Cassaro1,2, Pietro Impellizzeri1, Giulia Maisano1
1Unit of Pediatric Surgery, Department of Human Pathology of Adult and Childhood "Gaetano Barresi", University of Messina, 98125, Messina, Italy.
Insights
Enhanced Recovery After Surgery (ERAS) protocols significantly reduce complications and hospital stays in pediatric urological reconstructive surgery. This evidence supports standardizing ERAS for improved pediatric surgical outcomes.
Area of Science:
- Pediatric Surgery
- Urology
- Surgical Protocols
Background:
- Enhanced Recovery After Surgery (ERAS) protocols minimize surgical stress and shorten recovery.
- Previous studies indicated ERAS effectiveness in pediatric gastrointestinal surgery.
- The application of ERAS in pediatric urological reconstructive surgery requires further evaluation.
Purpose of the Study:
- To systematically review and meta-analyze the benefits of ERAS protocols in pediatric urological reconstructive surgery.
- To compare ERAS with traditional protocols regarding patient outcomes.
- To assess the safety and feasibility of ERAS in this specific pediatric surgical population.
Main Methods:
- Systematic literature search on PubMed for studies comparing ERAS and traditional protocols.
- Meta-analysis of data including major/minor complications, hospital readmission, and length of stay.
- Statistical analysis using Odds Ratios (OR) with 95% Confidence Intervals (Cl), with p < 0.05 considered significant.
Main Results:
- 10 studies with 1410 patients (492 ERAS, 918 No-ERAS) were included.
- ERAS significantly reduced major complications (p < 0.001) and length of hospital stay (p < 0.001).
- ERAS also decreased the incidence of minor complications (p = 0.002) without affecting hospital readmission rates (p = 0.763).
Conclusions:
- The ERAS protocol is safe and feasible for pediatric reconstructive urological surgery.
- ERAS implementation leads to reduced complication risks and shorter hospital stays.
- Standardizing ERAS procedures in pediatric reconstructive urology is recommended.
Abstract:
Enhanced Recovery After Surgery (ERAS) is a protocol that includes rules aimed to minimize surgical stress and to reduce the post-operative period. Initially applied in intestinal surgery of adults, a recent meta-analysis suggested that ERAS is valid also in pediatric gastrointestinal surgery. This study systematically reviewed and performed a meta-analysis to evaluate ERAS benefits in pediatric urological reconstructive surgery. A PubMed search identified studies comparing ERAS and traditional protocols in pediatric urological reconstructive surgery. Data on major and minor complications, hospital readmission, and length of hospital stay were collected and analyzed. Analyses were performed using OR and Cl 95%. A p-value < 0.05 was considered significant. A total of 10 papers met the inclusion criteria, with 1410 included patients (492 ERAS group, 918 No-ERAS). There were significant differences in major complications (p < 0.001) and length of stay (p < 0.001) and the incidence of minor complications (p = 0.002) favoring patients undergoing ERAS protocol; differently, there was no difference in hospital readmission (p = 0.763). ERAS protocol is safe and feasible for children undergoing reconstructive urological surgery, reducing the risks of complications and the length of hospital stay, without increasing readmission risk. ERAS should also be a standardized procedure in pediatric reconstructive urological surgery.
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