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Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also called...

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Updated: Jun 18, 2026

Light-mediated Formation and Patterning of Hydrogels for Cell Culture Applications

Light-mediated Formation and Patterning of Hydrogels for Cell Culture Applications

Published on: September 29, 2016

A Recent Review on Stimuli-Responsive Hydrogel Photonic Materials.

Yajie Wang¹, Jinnan Liu¹, Mengfan Yang¹

¹State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, 215123, China.

Macromolecular Rapid Communications

|April 10, 2025

Summary

Scientists create advanced hydrogel photonic materials that change color with environmental shifts. These stimuli-responsive materials offer exciting potential for visual sensing and anti-counterfeiting technologies.

Keywords:

hydrogels photonic materials sensing stimuli‐responsive polymers

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Area of Science:

Materials Science
Optics
Nanotechnology

Background:

Nature's structural colors inspire advanced photonic materials.
Stimuli-responsive hydrogel photonic materials are emerging for dynamic applications.

Purpose of the Study:

Review recent advancements in stimuli-responsive hydrogel photonic materials.
Focus on classification, manufacturing, and applications.
Highlight unique optical properties and stimuli-sensitivity.

Main Methods:

Detailed descriptions of photonic materials across different dimensions.
Outline innovative technologies for creating diverse photonic structures.
Analysis of sensitivity to temperature, humidity, pH, light, and mechanical force.

Main Results:

Materials exhibit dynamic structural and performance adjustments.
Demonstrated potential in visual sensing, anti-counterfeiting, and drug delivery.
Identified key optical properties derived from periodic microstructures.

Conclusions:

Stimuli-responsive hydrogel photonic materials offer versatile functionalities.
Current challenges and future prospects in manufacturing and application are examined.