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Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating...
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Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
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Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
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Interdisciplinary Approach to Developing Nicotine Dependence Treatment Order Set: An Innovative Pilot Implementation.

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This summary is machine-generated.

A new electronic health record system significantly increased healthcare providers

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Area of Science:

  • Public Health
  • Health Services Research
  • Behavioral Medicine

Background:

  • Tobacco use is a leading cause of preventable death in the U.S.
  • State quitlines are effective tobacco cessation interventions but have low referral rates.
  • A gap exists in integrating quitline referrals into clinical practice.

Purpose of the Study:

  • To develop and evaluate a new electronic health record-based referral system for nicotine dependence treatment.
  • To improve patient referral rates to state quitlines and community resources.
  • To assess the usability and adoption potential of the new system among healthcare providers.

Main Methods:

  • Stakeholder feedback was gathered to update an existing nicotine dependence order set (NDO).
  • The updated NDO included links to state quitlines and social determinants of health resources.
  • Surveys measured intention to use, acceptance, appropriateness, and feasibility before and after dissemination to leadership and clinicians.

Main Results:

  • Pre-intervention, only 10-13% of providers used the existing NDO.
  • Post-intervention, nearly 100% of providers intended to use the new NDO.
  • Acceptance, appropriateness, and feasibility were rated highly by both leadership and clinicians.

Conclusions:

  • The new electronic health record-based NDO shows high potential for improving tobacco cessation referrals.
  • Provider intention to use and perceived usability are strong.
  • Further research is needed to confirm adoption, sustainability, and impact on smoking cessation outcomes.