Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic active hepatitis. Prolonged survival without treatment.

T O Lipman, L B Seeff, W O Dobbins

    The American Journal of Digestive Diseases
    |January 1, 1977
    PubMed
    Summary

    This case study highlights a patient with long-term HBsAg-positive chronic active hepatitis and cirrhosis who experienced minimal disability without treatment. It suggests corticosteroid therapy may not be essential for all chronic hepatitis B patients.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Silymarin use and liver disease progression in the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis trial.

    Alimentary pharmacology & therapeutics·2010
    Same author

    The course of hepatitis C viraemia in transfusion recipients prior to availability of antiviral therapy.

    Journal of viral hepatitis·2008
    Same author

    Epidemiology of hepatocellular carcinoma in areas of low hepatitis B and hepatitis C endemicity.

    Oncogene·2006
    Same author

    Strategies for assessing the long-term consequences of Hepatitis C virus infection.

    Minerva gastroenterologica e dietologica·2006
    Same author

    The natural history of chronic hepatitis C virus infection.

    Clinics in liver disease·2004
    Same author

    AGA technical review on parenteral nutrition.

    Gastroenterology·2001

    Area of Science:

    • Hepatology
    • Virology
    • Immunology

    Background:

    • Chronic active hepatitis B (CAH) is a significant global health concern.
    • Hepatitis B surface antigen (HBsAg) positivity indicates persistent infection.
    • Cirrhosis represents advanced liver scarring, often associated with significant morbidity.

    Observation:

    • A unique case of HBsAg-positive chronic active hepatitis and cirrhosis is presented.
    • The patient maintained a relatively low disability level despite a 14-year disease duration.
    • No specific treatment was administered during the observation period.

    Findings:

    • Prolonged disease course in chronic hepatitis B can present with varying levels of disability.
    • This case challenges the assumption of mandatory corticosteroid treatment for all CAH patients.
    • Individual patient response and disease progression can differ significantly.

    Implications:

    • Corticosteroid therapy might not be universally required for managing HBsAg-positive chronic active hepatitis and cirrhosis.
    • Further research is needed to identify predictors of benign disease progression in chronic hepatitis B.
    • Personalized treatment strategies may be more effective for managing chronic liver diseases.

    Related Experiment Videos