Updates in perioperative hemostasis in the pediatric surgical patient

Michael Richard Greenberg1, Edmund Jooste, Natalia Diaz-Rodriguez

  • 1Division of Pediatric Anesthesiology, Duke University, Durham, North Carolina, USA.

Insights

Pediatric patient blood management (PBM) programs are gaining traction, focusing on anemia treatment and restrictive transfusion thresholds. Evidence supports reducing allogeneic blood products in pediatric surgery, though more research is needed.

Area of Science:

  • Anesthesiology
  • Pediatric Surgery
  • Hematology

Background:

  • Pediatric perioperative bleeding and hemostasis management present unique challenges.
  • Patient blood management (PBM) programs are crucial for optimizing outcomes.

Purpose of the Study:

  • To review recent updates in pediatric perioperative bleeding and hemostasis management.
  • To highlight advancements in patient blood management strategies for pediatric surgical patients.

Main Methods:

  • Literature review of recent evidence on pediatric PBM.
  • Analysis of studies on restrictive transfusion thresholds and allogeneic blood product reduction.
  • Evaluation of viscoelastic testing and whole blood use in pediatric populations.

Main Results:

  • Growing evidence supports restrictive transfusion thresholds and reduced allogeneic blood use in children.
  • Pediatric PBM programs show promise in treating anemia and optimizing coagulation.
  • Viscoelastic testing and whole blood show efficacy in pediatric settings.

Conclusions:

  • Patient blood management components, including anemia treatment and restrictive transfusion, are increasingly adopted in pediatric care.
  • Further evidence is required to guide anesthesiologists in pediatric hemostasis management.
  • Optimizing coagulation and tolerating physiologic anemia are key PBM strategies.
Abstract

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