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Related Concept Videos

Pulse rhythm01:30

Pulse rhythm

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Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
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Heart Failure VI: Adjunct Therapies01:22

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Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
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Related Experiment Video

Updated: May 5, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
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First-in-Human Implantable Inferior Vena Cava Sensor for Remote Care in Heart Failure: FUTURE-HF.

Paul R Kalra1, Irakli Gogorishvili2, George Khabeishvili3

  • 1Department of Cardiology, Queen Alexandra Hospital, Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom.

JACC. Heart Failure
|April 10, 2025
PubMed
Summary

A new implantable sensor for monitoring the inferior vena cava (IVC) is safe and feasible for heart failure (HF) patients. This technology accurately measures IVC area, potentially improving remote management of congestion and HF events.

Keywords:
FUTURE-HFcongestion monitoringheart failureinferior vena cava sensorremote carevolume status

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Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Devices

Background:

  • Inferior vena cava (IVC) variations indicate fluid overload and predict heart failure (HF) events.
  • Early detection of congestion is crucial for managing HF patients.

Purpose of the Study:

  • To assess the safety and feasibility of a novel implantable IVC sensor for remote HF management.
  • To report on primary (3-month) and exploratory (6-month) endpoints of the FUTURE-HF trial.

Main Methods:

  • Implantation of an IVC sensor in 50 HF patients.
  • Evaluation of safety, procedural success, and signal acquisition.
  • Comparison of sensor-derived IVC area with CT measurements.
  • Assessment of patient adherence and clinical outcomes at 6 months.

Main Results:

  • Successful implantation in all patients; 49 met primary endpoints.
  • Excellent agreement between sensor-derived and CT-derived IVC area (R² = 0.98).
  • High patient adherence (median 96%) and promising exploratory clinical outcomes.

Conclusions:

  • Implantation of the IVC sensor is safe and feasible in HF patients.
  • The sensor accurately measures IVC area, correlating well with CT.
  • This technology shows potential for ambulatory congestion management and remote HF care.