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Updated: Jul 8, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Concomitant Mitral Transcatheter Edge-to-Edge Repair and Transcatheter Closure of Perforated Anterior Mitral Valve
Shriya K Prakash1, Caitlyn Andreas1, Chloe Kharsa1
1Department of Cardiology, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Abstract:
We present the case of a 76-year-old man with a previous history of surgical aortic valve replacement 3 years earlier for infective endocarditis, nonischemic cardiomyopathy, and severe secondary mitral regurgitation (SMR) who presented with worsening dyspnea on exertion. Echocardiography revealed severe SMR and a perforation at the base of the A1 scallop of the anterior mitral valve leaflet (AMVL). The patient was deemed at high surgical risk. After multidisciplinary team discussion, we proceeded with mitral transcatheter edge to edge repair with 2 MitraClips (Abbott) and concomitant transcatheter closure of the perforation of the AMVL with an Amplatzer Duct Occluder II (Abbott) device.
Insights
This case study details a minimally invasive transcatheter repair for severe mitral regurgitation and a perforated mitral valve leaflet, offering a high-risk option for complex cardiac conditions.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Cardiac Surgery
Background:
- A 76-year-old male with prior aortic valve replacement, nonischemic cardiomyopathy, and severe secondary mitral regurgitation (SMR) presented with exertional dyspnea.
- Echocardiography identified severe SMR and a critical perforation in the anterior mitral valve leaflet (AMVL).
- The patient was deemed high-risk for conventional open-heart surgery.
Related Concept Videos
Mitral Valve Prolapse I: Introduction
Mitral Valve Prolapse II: Assessment and Management
Mitral Regurgitation I: Introduction
Mitral Regurgitation III: Medical Management
Mitral Stenosis I: Introduction
Mitral Stenosis III: Medical Management

