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Transplantation of Autologous Dermo-Epidermal Skin Substitutes in a Pig Model
Thea Fleischmann1, Flora Nicholls1,2, Miriam Lipiski1,2
1Biological Central Laboratory & Division of Surgical Research, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Abstract:
Due to its similarity of skin anatomy and physiology, the pig appears to be a well-suited animal model for pre-clinical studies of skin analogue transplantations. The choice of the location of the skin defect and appropriate post-operative measures are essential for the protection of the transplanted graft. This protocol describes in detail a porcine skin transplantation model including peri- and postoperative measures taken to improve and refine the studies outcome.

