En Route to Anthanthrenes through Bottom-up APEX Strategy by peri-C-H Activation
Abhisek Metya1, Supreeta Sen1, Arya Bhattacharyya1
1Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Abstract:
Accessing PAHs having all zigzag edges remains elusive, and this work demonstrates a general synthetic strategy for the construction of one such scaffold, namely, anthanthrene, through Ru(II)-catalyzed APEX reaction at the masked-bay region. The protocol efficiently delivers a range of uniquely substituted anthanthrenes with excellent regioselectivity, which is supported by DFT studies. The synthesis of anthanthrone derivatives, a core structure of vat orange dyes, is another highlight of this study.
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