Related Experiment Video
Updated: Jul 19, 2026

Trypsinizing and Subculturing Mammalian Cells
Published on: June 12, 2008
Abstract:
Dr. Tychele Turner is an assistant professor of genetics at the Washington University in St. Louis. This issue of Cell Genomics presents research from her lab in "Proteome-wide assessment of differential missense variant clustering in neurodevelopmental disorders and cancer" by Ng et al. This paper used their newly developed program, 3D-CLUMP, which can perform proteome-wide significant case-control analysis and clustering of protein-coding variants related to disease. Using 3D-CLUMP, they examine how patients with mostly cancer or neurodevelopmental disorders (NDDs) are observed to have the same gene, even if the specific mutations causing them are not shared.
More Related Videos
09:39Generation of Induced Pluripotent Stem Cells from Turner Syndrome (45XO) Fetal Cells for Downstream Modelling of Neurological Deficits Associated with the Syndrome
Published on: December 4, 2021
11:003D Flipwell Engineering for Developing Asynchronous Systems for Toxicologic and Immunomodulatory Therapies in Bacterial, Gut, and Immune Cells
Published on: October 17, 2025
Related Concept Videos
Phosphorylation
During phosphorylation, protein kinases transfer the terminal phosphate group of ATP to specific amino acid side chains of substrate proteins. Serine, threonine, and tyrosine are the most commonly...
Nature and Nurture
The Phosphorus Cycle
Life Histories
Phylogeny
Stereotype Threat and Self-fulfilling Prophecies