Recurrence Screening of Undifferentiated Pleomorphic Sarcoma with Giant Cells of the Breast

Undifferentiated pleomorphic sarcoma (UPS) of the breast is a rare mesenchymal tumor that is not commonly encountered in clinical settings. Given its high recurrence rate, close monitoring, and follow-up are strongly recommended.

In this case, the recurrence of UPS with giant cells of the breast was screened through ultrasound imaging and tumor marker tests, including CA 15-3 and CA 72-4.

Following recurrence, the patient achieved partial clinical remission after six cycles of epirubicin-based adjuvant chemotherapy. In accordance with the patient's preference, a left mastectomy was performed. Postoperatively, the patient's condition stabilized, with a smooth and satisfactory recovery.

This case demonstrates that the combined evaluation of abnormal carbohydrate antigen expression and ultrasound features can enhance the diagnostic accuracy of suspected recurrent nodules following surgery for UPS of the breast.