The next generation of regression standardization with the R package stdReg2

Michael C Sachs1, Johan Sebastian Ohlendorff1, Adam Brand2

  • 1University of Copenhagen, Section of Biostatistics, Øster Farimagsgade 5, Copenhagen, Denmark.

Annals of Epidemiology
|April 10, 2025
PubMed
Summary

The R package stdReg2 enhances causal inference in epidemiology with improved user-friendliness and new double-robust methods for average treatment effect estimation. This updated statistical software offers greater flexibility for researchers.

Related Concept Videos

Regression Toward the Mean01:52

Regression Toward the Mean

Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...
6.3K
Regression Analysis01:11

Regression Analysis

Regression analysis is a statistical tool that describes a mathematical relationship between a dependent variable and one or more independent variables.
In regression analysis, a regression equation is determined based on the line of best fit– a line that best fits the data points plotted in a graph. This line is also called the regression line. The algebraic equation for the regression line is called the regression equation. It is represented as:
5.5K
Estimating Population Standard Deviation01:26

Estimating Population Standard Deviation

When the population standard deviation is unknown and the sample size is large, the sample standard deviation s is commonly used as a point estimate of σ. However, it can sometimes under or overestimate the population standard deviation. To overcome this drawback, confidence intervals are determined to estimate population parameters and eliminate any calculation bias accurately. However, this only applies to random samples from normally distributed populations. Knowing the sample mean and...
3.0K
Multiple Regression01:25

Multiple Regression

Multiple regression assesses a linear relationship between one response or dependent variable and two or more independent variables. It has many practical applications.
Farmers can use multiple regression to determine the crop yield based on more than one factor, such as water availability, fertilizer, soil properties, etc. Here, the crop yield is the response or dependent variable as it depends on the other independent variables. The analysis requires the construction of a scatter plot...
2.9K
Estimating Population Mean with Known Standard Deviation01:16

Estimating Population Mean with Known Standard Deviation

To construct a confidence interval for a single unknown population mean μ, where the population standard deviation is known, we need sample mean as an estimate for μ and we need the margin of error. Here, the margin of error (EBM) is called the error bound for a population mean (abbreviated EBM). The sample mean is the point estimate of the unknown population mean μ.
The confidence interval estimate will have the form as follows:
(point estimate - error bound, point estimate +...
8.2K
Testing a Claim about Standard Deviation01:19

Testing a Claim about Standard Deviation

A complete procedure to test a claim about population standard deviation or population variance is explained here.
The hypothesis testing for the claim of population standard deviation (or variance) requires the data and samples to be random and unbiased. The population distribution also must be normal. There is no specific requirement on the sample size as the estimation is based on the chi-square distribution.
As a first step, the hypothesis (null and alternative) concerning the claim about...
2.4K