Related Experiment Video
Updated: May 15, 2025

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
Clinical Characteristics and Treatment of Histiocytic Disorders in Children
Barbara A Degar1, Jennifer T Huang2, Jacob Bledsoe3
1Department of Pediatrics, Harvard Medical School, Boston, MA 02215, USA; Department of Pediatric Oncology, Dana-Farber Cancer Institute / Boston Children's Cancer and Blood Disease Center, 450 Brookline Avenue, Boston, MA 02215, USA.
Abstract:
Several distinct histiocytic neoplasms occur in children. These diseases are rare and their behavior is remarkably variable. In this article, the clinical and histopathologic features of Langerhans cell histiocytosis, Juvenile Xanthogranuloma, Rosai-Dorfman-Destombes, and ALK + Histiocytosis are reviewed. Recommendations for diagnostic evaluation of these entities are included and treatment approaches are presented.
More Related Videos
09:51Development and Functional Characterization of Murine Tolerogenic Dendritic Cells
Published on: May 18, 2018
06:08Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model
Published on: February 10, 2023
Related Concept Videos
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Regulation of Hematopoietic Stem Cells
Lysosomal Hydrolases