Cardiac history and post-stroke depression association in Chinese stroke survivors: a cross sectional study

Longxiao Liu1,2, Peng Qin2, Jing Bai1,2

  • 1Tianjin University of Traditional Chinese Medicine, 88 Changling Road, Tianjin, 301617, China.

Scientific Reports
|April 10, 2025
PubMed

Insights

A history of cardiac disease significantly increases the risk of developing post-stroke depression (PSD). Early identification and intervention are crucial for improving outcomes in stroke patients with cardiac conditions.

Area of Science:

  • Neurology
  • Cardiology
  • Psychiatry

Background:

  • Stroke is a leading global cause of death and disability.
  • Post-stroke depression (PSD) negatively impacts patient prognosis.
  • Early identification and prevention of PSD are critical.

Purpose of the Study:

  • To investigate the association between cardiac history and PSD in Chinese stroke patients.
  • To identify high-risk populations for PSD.
  • To inform early intervention strategies and enhance patient outcomes.

Main Methods:

  • Utilized data from the 2020 China Health and Retirement Longitudinal Study (CHARLS).
  • Included 933 stroke patients with a history of stroke.
  • Employed univariate and multivariate logistic regression analyses.

Main Results:

  • A significant correlation was found between cardiac history and PSD.
  • Factors such as gender, ADLs, cognitive function, and life satisfaction also influenced PSD.
  • Patients with prior cardiac disease showed a higher likelihood of developing PSD.

Conclusions:

  • Cardiac history is a key risk factor for post-stroke depression.
  • Clinical management should prioritize emotional health assessment for stroke patients with cardiac conditions.
  • Psychological support and interventions are essential for improving prognosis.