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Urination Stimulation Techniques for Collecting Clean Urine Samples in Infants Under One Year: Systematic Review and

Francisco Javier Gómez-Manzano1,2,3, Esperanza Barroso-Corroto2,3,4, José Alberto Laredo-Aguilera2,3,4

  • 1Centro Integrado Formación Profesional n1, Consejería de Educación, Cultura y Deportes de Castilla-La Mancha, Toledo, Spain.

Acta Paediatrica (Oslo, Norway : 1992)
|April 11, 2025
PubMed

Insights

Spontaneous urination stimulation techniques are effective for collecting valid infant urine samples quickly. These methods are particularly successful in infants under six months old.

Area of Science:

  • Pediatrics
  • Urology
  • Clinical Diagnostics

Background:

  • Obtaining uncontaminated urine samples from infants is challenging.
  • Traditional methods can be invasive or time-consuming.
  • Effective sample collection is crucial for accurate diagnosis.

Purpose of the Study:

  • To evaluate the efficacy of spontaneous urination stimulation techniques.
  • To assess the success and contamination rates of these methods in infants under one year.
  • To determine the optimal age range for these techniques.

Main Methods:

  • Systematic review of randomized clinical trials.
  • Searched multiple databases including PubMed, Scopus, Web of Science, CINAHL, and Virtual Health Library.
  • Meta-analysis of success and contamination rates, with risk of bias assessment using RoB2 scale.

Main Results:

  • Seven studies involving 1122 infants were included.
  • Urination stimulation techniques (Herreros et al. and Quick-Wee) were effective in obtaining samples.
  • Success was defined as a midstream urine sample in under 5 minutes, especially in infants < 6 months.

Conclusions:

  • Stimulating urination is a noninvasive, fast, safe, and economical method for infant urine sample collection.
  • This technique yields valid midstream samples suitable for analysis.
  • It offers a reliable alternative for pediatric urine diagnostics.
Abstract

Keywords:
clean urine captureinfanturination stimulation

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