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Frozen Cadaveric Rib Grafts in Primary or Revision Rhinoplasty: A Systematic Review and Meta-analysis.

Mohamed Amir Mrad¹, Abdullah A Al Qurashi^2,3, Qutaiba N M Shah Mardan^3,4

¹From the Plastic and Reconstructive Surgery Section, Department of Surgery, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

Plastic and Reconstructive Surgery. Global Open

|April 11, 2025

Summary

This summary is machine-generated.

Fresh frozen cadaveric rib grafts are a viable option for rhinoplasty, showing low complication rates. However, long-term follow-up and revision rhinoplasty cases indicate higher complication risks, necessitating careful monitoring.

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Area of Science:

Plastic Surgery
Otolaryngology
Biomaterials Science

Background:

Cartilage grafts are crucial for rhinoplasty framework support.
Autologous and irradiated homologous cartilage have limitations.
Fresh frozen cadaveric rib grafts offer a promising alternative, potentially reducing complications.

Purpose of the Study:

To conduct a meta-analysis assessing outcomes of fresh frozen cadaveric rib grafts in primary and revision rhinoplasty.
To provide a comprehensive evaluation of complication rates associated with these grafts.

Main Methods:

Systematic review and meta-analysis of studies published up to January 2023.
Searched MEDLINE, Embase, Scopus, Cochrane, and ClinicalTrials.gov.
Pooled data from 5 studies involving 440 patients using a random-effects model.

Main Results:

Overall complication rate was low.
Higher complication rates observed in studies with longer follow-up (7.6%).
Revision rhinoplasty cases showed a higher complication rate (12.7%).

Conclusions:

Fresh frozen cadaveric costal cartilage is suitable for rhinoplasty with generally low complications.
Longer follow-up and revision cases warrant caution due to increased complication rates.
Extended postoperative monitoring is recommended for accurate long-term outcome assessment.