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Updated: May 15, 2025

Thoracic Spinal Cord Hemisection Surgery and Open-Field Locomotor Assessment in the Rat
Published on: June 26, 2019
Thoracic SMARCA4-deficient undifferentiated tumor
Yukina Izumi1, Yuko Sano1, Kaori Yamada1
1Department of Diagnostic Radiology, Japanese Red Cross Kyoto Daiichi Hospital, Kyoto, Japan.
Abstract:
Thoracic SMARCA4-deficient undifferentiated tumor (SMARCA4-UT) is characterized by an undifferentiated rhabdoid morphology and SMARCA4 deficiency pathologically. In the 2021 revision of the WHO classification, it was categorized as an epithelial tumor because of its shared genetic background with smoking-related lung cancer. We describe the case of a 44-year-old man with a rapidly enlarging mediastinal mass observed on chest radiography and CT. The tumor was resistant to radiation therapy, chemotherapy, and immune checkpoint inhibitors, and the patient's survival time was approximately 5 months. Familiarity with the clinical background and imaging findings of thoracic SMARCA4-UT is crucial for early diagnosis and treatment planning.
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