Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

368
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
368
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

397
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
397

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Quantitative Analysis of Retinal Fluid by a Deep Learning Model in Uveitic Macular Edema.

Ophthalmology science·2026
Same author

Operating Room Energy Usage Assessment at a Tertiary Academic Medical Center in the United States.

Anesthesia and analgesia·2026
Same author

Diagnostic Performance of Prespecified OCT Rules for Glaucomatous Optic Neuropathy in Nonpathologic Myopia.

JAMA ophthalmology·2026
Same author

Tandem Duplication-Driven Neofunctionalization of UDP-Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

The Effects of a Digital Mindfulness Intervention on Mental Health and Vision-Related Quality of Life in Non-infectious Uveitis.

Ophthalmology·2026
Same author

Quality of Life Following Modified Radical Mastectomy for Breast Cancer in Haiti.

JCO global oncology·2026

Related Experiment Video

Updated: May 15, 2025

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

2.6K

Impact of the Coronavirus Disease 2019 Pandemic on Initiation Therapy for Noninfectious Uveitis.

Evan M Chen1, D Claire Miller1, Yuwei Sun1

  • 1F.I. Proctor Foundation, Department of Ophthalmology, University of California, San Francisco, San Francisco, California.

Ophthalmology Science
|April 11, 2025
PubMed
Summary

The COVID-19 pandemic did not significantly alter noninfectious uveitis (NIU) treatment patterns. However, topical and local steroid use for NIU increased during the early pandemic period.

Keywords:
COVID-19InflammationTreatment medicalUveitis

More Related Videos

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
07:40

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Published on: January 12, 2022

4.6K
Subconjunctival Administration of Adeno-associated Virus Vectors in Small Animal Models
06:16

Subconjunctival Administration of Adeno-associated Virus Vectors in Small Animal Models

Published on: March 16, 2022

2.8K

Related Experiment Videos

Last Updated: May 15, 2025

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

2.6K
Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
07:40

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Published on: January 12, 2022

4.6K
Subconjunctival Administration of Adeno-associated Virus Vectors in Small Animal Models
06:16

Subconjunctival Administration of Adeno-associated Virus Vectors in Small Animal Models

Published on: March 16, 2022

2.8K

Area of Science:

  • Ophthalmology
  • Immunology
  • Public Health

Background:

  • The COVID-19 pandemic raised concerns about the safety of immunomodulatory therapy (IMT) due to potential increased infection risks.
  • Understanding the pandemic's impact on noninfectious uveitis (NIU) treatment is crucial for patient management.

Purpose of the Study:

  • To evaluate how the COVID-19 pandemic influenced treatment strategies for noninfectious uveitis (NIU).

Main Methods:

  • Retrospective analysis of a large US healthcare database (Optum Labs Data Warehouse).
  • Interrupted time series (ITS) analysis was used to model prescription rates of NIU therapies across prepandemic, early pandemic, and postvaccine periods.
  • Cox proportional hazard models assessed differences in treatment modality likelihood between periods.

Main Results:

  • No significant changes in prescribing trends for topical, local, or systemic corticosteroids and immunosuppressive therapies were observed between pandemic periods.
  • Topical steroid prescriptions for NIU increased during the early pandemic compared to the prepandemic period.
  • Intraocular steroid use also increased during the early and postvaccine periods, while immunomodulatory therapy (IMT) use rose in the postvaccine period.

Conclusions:

  • The COVID-19 pandemic did not lead to significant shifts in overall NIU treatment patterns.
  • There was a notable increase in the utilization of topical and local steroids for NIU during the early phase of the pandemic.