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Investigating the effect of SARS-CoV-2 on the sperm parameters
Hadi Maleki1, Mahshid Bazrafkan2, Behrouz Fatahi1
1Department of Urology, School of Medicine, Shahid Madani Hospital, Alborz University of Medical Sciences, Karaj, Iran.
Annals of Medicine and Surgery (2012)
|April 11, 2025
Summary
COVID-19 significantly decreased sperm concentration, total count, and morphology in men. While motility and volume remained unchanged, these findings highlight the virus's adverse impact on male reproductive health.
Area of Science:
- Reproductive Medicine
- Virology
- Men's Health
Background:
- COVID-19, caused by SARS-CoV-2, may negatively impact male reproductive health.
- The virus can affect spermatogenesis and overall testicular function.
Purpose of the Study:
- To analyze changes in semen parameters in men before and after the COVID-19 pandemic.
- To assess the long-term effects of SARS-CoV-2 infection on male fertility.
Main Methods:
- A cross-sectional study involving 150 men was conducted.
- Semen parameters (volume, count, motility, viability, morphology, concentration) were analyzed 3-12 months post-infection.
- Demographic and medical data were extracted from patient records.
Main Results:
- Sperm concentration and total sperm count significantly decreased post-COVID-19.
- Sperm morphology also showed a significant decline.
- Semen volume and sperm motility remained statistically unchanged.
Conclusions:
- SARS-CoV-2 infection can adversely affect male reproductive health.
- Understanding these effects is crucial for developing targeted treatments.
- Effective therapies can reduce disease-related costs and improve fertility rates.
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