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Updated: May 14, 2025

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
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Development and Evaluation of a Multifaceted Intervention Program for Preventing Medication Administration Errors by

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  • 1Department of Nursing, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.

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|April 11, 2025
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Summary

A new intervention program based on the Systems Engineering Initiatives for Patient Safety (SEIPS) model significantly improved nurses' patient safety culture and medication safety compliance. While direct medication administration error (MAE) rates did not change, the study validates a systems-based approach to improving medication safety.

Keywords:
medication errorsnursespatient safetyprogram developmentsafety management

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Area of Science:

  • Nursing
  • Patient Safety
  • Healthcare Systems Engineering

Background:

  • Medication administration errors (MAEs) are a significant concern in healthcare.
  • Existing interventions often focus on individual performance rather than systemic factors.

Purpose of the Study:

  • To develop and evaluate a multifaceted intervention program using the Systems Engineering Initiatives for Patient Safety (SEIPS) model.
  • To prevent MAEs among nurses in a hospital setting.

Main Methods:

  • The intervention program was developed using the Analysis, Design, Development, Implementation, Evaluation (ADDIE) model and expert Delphi surveys.
  • A pretest-posttest design with 73 nurses (experimental and control groups) was employed.
  • Patient safety culture, medication safety practices, and error rates were assessed before and after a 3-month intervention.

Main Results:

  • Significant improvements were observed in patient safety culture perception (P <0.001) and medication safety compliance (P <0.001).
  • Large effect sizes were noted for both improved culture and compliance.
  • No statistically significant change in self-reported MAE rates was found, potentially due to the short intervention duration.

Conclusions:

  • The SEIPS-based intervention effectively enhanced nurses' patient safety awareness and medication safety compliance.
  • The study underscores the value of theoretically grounded, systems-level interventions for improving medication safety.
  • Future efforts should focus on addressing systemic issues beyond individual nurse education to further reduce MAEs.