Related Experiment Video
Updated: May 3, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
Antihypertensive Medication Adherence and Related Factors among Elderly Hypertensive Patients in China: A
Haiyan Liu1, Xueqin Zuo2, Zhikai Zhou2
1Assistant Professor, Department of Preventive Medicine, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China.
Background:
Hypertension is one of the most common chronic diseases among elderly people, while medication adherence is associated with a decreased risk of complications in elderly hypertensive patients.
Objectives:
The purpose of this meta-analysis was to estimate the adherence to antihypertensive medication and related factors in elderly hypertensive patients in China.
Materials And Methods:
The databases served to retrieve the relevant literature before May 31, 2023. A systematic review (PROSPERO-CRD 42021278970) was conducted in accordance with PRISMA (Preferred Reporting Item for Systematic Reviews and Meta Analyses). Subgroup analysis, I2 statistics, publication bias, and quality assessment were conducted.
Results:
The prevalence of medication adherence among old hypertensive patients in China was 43% (95% confidence interval [CI]: 37%-49%). Medication adherence was related to education level (odds ratio [OR] = 2.12, 95% CI: 1.46-3.08), marriage (OR = 1.37,95% CI: 1.09-1.72) and the nonpresence of comorbidities (OR = 1.55, 95% CI: 1.11-2.16), but not related to the course of the disease ≤5 years (OR = 0.91,95% CI: 0.67-1.24). Adherence to antihypertensive medication among the old hypertensive population in China was moderate.
Conclusion:
Healthcare professionals should attach importance to older hypertension patients with low level of education and no spouse.
Related Concept Videos
Factors affecting Blood pressure
Physiological Factors:
Drug Dosing: Geriatric Patients
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion
Pharmacodynamics in Geriatric Patients: Effects of Age

