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Related Concept Videos

Pleural Effusion II: Symptoms and Management01:28

Pleural Effusion II: Symptoms and Management

135
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
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Pleural Effusion I: Introduction01:25

Pleural Effusion I: Introduction

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Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
311
Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

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The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
166
Pneumothorax-II01:27

Pneumothorax-II

107
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
107
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

268
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
268
Pleura of the Lungs01:13

Pleura of the Lungs

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The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
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Related Experiment Video

Updated: May 14, 2025

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
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Myelomatous pleural effusion: An atypical initial presentation.

Simran J Thakkar1, Namita Padwal, Niteen Karnik

  • 1Department of Medicine, Lokmanya Tilak Municipal Medical College, Mumbai, Maharashtra, India.

Journal of Cancer Research and Therapeutics
|April 11, 2025
PubMed
Summary

Malignant pleural effusion is rare in multiple myeloma (MM). This case highlights MM presenting initially with massive pleural effusion, lung mass, renal failure, and anemia, indicating a poor prognosis.

Area of Science:

  • Oncology
  • Hematology
  • Pulmonology

Background:

  • Malignant pleural effusion typically arises from metastatic lung, breast, ovarian cancers, sarcomas, lymphomas, or mesothelioma.

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  • Pleural effusion as an initial presentation of multiple myeloma (MM) is exceptionally rare, accounting for less than 1% of cases.
  • This rare presentation is often linked to a poor patient prognosis.