Related Experiment Video
Updated: Jun 28, 2026
Modeling the Early Steps of Ovarian Cancer Dissemination in an Organotypic Culture of the Human Peritoneal Cavity
Published on: December 31, 2015
Multicystic peritoneal mesothelioma with floret-like multinucleated giant cells: A case report
Robert Ricardo Rodríguez Carpio1, Carlos Hörndler Argarate1, Sandra Vicente Arregui1
1Servicio de Anatomía Patológica, Hospital Universitario Miguel Servet, Zaragoza, Spain.
Abstract:
Multicystic peritoneal mesothelioma is an uncommon neoplasm characterized by multiple cysts adhering to the abdominal cavity. The symptoms are nonspecific, and their severity appears to be related to the size and location of the cysts. We report the case of a 55-year-old man with morbid obesity in whom a multiloculated mesenteric mass was incidentally discovered on abdominal ultrasound. Complementary imaging studies revealed a multicystic peritoneal tumour with a maximum diameter of 32cm, located in the pelvis and extending to the right hemiabdomen. Histologically, multiple cysts lined by mesothelial cells without atypia were observed, along with loose fibrous stroma containing numerous multinucleated floret-like giant cells. Based on the histopathological findings, the final diagnosis was multicystic peritoneal mesothelioma.
Insights
Multicystic peritoneal mesothelioma is a rare abdominal tumor. This case highlights its incidental discovery and characteristic histological findings in a morbidly obese patient.
Area of Science:
- Oncology
- Pathology
Background:
- Multicystic peritoneal mesothelioma is an uncommon neoplasm.
- It presents with nonspecific symptoms related to cyst size and location.
Observation:
- A 55-year-old man with morbid obesity presented with an incidentally discovered multiloculated mesenteric mass on ultrasound.
- Imaging revealed a large (32cm) multicystic peritoneal tumor in the pelvis and right hemiabdomen.
Findings:
- Histopathology showed multiple cysts lined by atypical mesothelial cells.
- The stroma contained numerous multinucleated floret-like giant cells.
Implications:
- This case expands understanding of multicystic peritoneal mesothelioma presentation.
- Accurate histopathological diagnosis is crucial for managing this rare tumor.
