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Normolipemic activities of acrylophenone derivatives with antimicrotubular properties
Abstract:
Acrylophenone derivatives with in vitro antimicrotubular activities very similar to those of colchicine were tested on Triton WR 1339-induced hyperlipidemia in rats. They exhibit high normolipemic activity on plasmatic apolipoproteins AI and B, contrasting with inactivity on plasmatic lipids and lipoproteins.