Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Arteries of the Lower Limbs01:24

Arteries of the Lower Limbs

168
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
168
Seizures: Classification01:13

Seizures: Classification

285
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
285
Antiepileptic Drugs: Glutamate Antagonists01:14

Antiepileptic Drugs: Glutamate Antagonists

252
Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
252
Antiepileptic Drugs: Sodium Channel Blockers01:08

Antiepileptic Drugs: Sodium Channel Blockers

270
Antiepileptic drugs are specialized medications that prevent seizures in individuals diagnosed with epilepsy. These drugs primarily function by blocking the movement of sodium ions through channels in the neuronal membrane, inhibiting the repetitive firing of action potentials often associated with seizures.
Sodium channel blockers modulate ion channels, particularly voltage-gated sodium channels. They block only sodium ion movement.
Among the most commonly prescribed antiepileptic drugs are...
270
Electroconvulsive Therapy01:30

Electroconvulsive Therapy

18
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
18
Antiepileptic Drugs: GABAergic Pathway Potentiators01:18

Antiepileptic Drugs: GABAergic Pathway Potentiators

264
γ-aminobutyric acid or GABA, plays a pivotal role as an inhibitory neurotransmitter in the brain. GABA pathway potentiators, also known as GABAergic drugs, are a class of pharmaceutical agents designed to enhance the functioning of the GABAergic system. These medications primarily treat epilepsy, a neurological disorder characterized by recurrent seizures.
The key GABA pathway potentiators used in epilepsy management are as follows.
Benzodiazepines are a well-known class of drugs used for...
264

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of field number and monitor units per segment on magnetic resonance-guided hypofractionated stereotactic radiotherapy for brain metastases: plan quality, deliverability, and robustness trade-offs.

Quantitative imaging in medicine and surgery·2026
Same author

A molybdenum-promoted nickel-aluminum alloy catalyst for high-efficient hydrogenation reduction of nitrate to ammonia and nitrogen.

RSC advances·2026
Same author

Triazine and other herbicides in sediments of lower Laurentian Great Lakes - pre- and post-depositional mobility and in-situ degradation.

Environmental pollution (Barking, Essex : 1987)·2026
Same author

Biomass-Derived Hydrogels for Load-Bearing Connective Tissue Repair: Integrative Reinforcement, Bio-Functional Design, and Emerging Pathways Toward Clinical Translation.

Advanced healthcare materials·2026
Same author

The Proliferation and Adipogenic/Fibrogenic Fate Commitment of FAPs via an Autocrine LAMA2/ITGβ1-FAK Pathway.

Journal of agricultural and food chemistry·2026
Same author

The influence of successful septal myectomy on myocardial stress distributions in the left ventricle: a computational analysis.

Biomedical engineering online·2026

Related Experiment Video

Updated: May 14, 2025

Manipulation of Epileptiform Electrocorticograms ECoGs and Sleep in Rats and Mice by Acupuncture
09:06

Manipulation of Epileptiform Electrocorticograms ECoGs and Sleep in Rats and Mice by Acupuncture

Published on: December 22, 2016

9.5K

Epilepsy in Asian countries.

Alhamdu Adamu1, Rui Chen1, An Li1

  • 1The Second Affiliated Hospital of Shanxi Medical University, Shanxi, 030001, Taiyuan, China.

Acta Epileptologica
|April 11, 2025
PubMed
Summary
This summary is machine-generated.

Managing epilepsy in Asia is challenging due to limited resources, affecting millions. Increased research and funding are crucial to bridge treatment gaps for epilepsy care in these communities.

Keywords:
AsiaCurrent situationEpilepsyTreatment

More Related Videos

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
09:57

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

2.5K
Electrophoretic Delivery of γ-aminobutyric Acid GABA into Epileptic Focus Prevents Seizures in Mice
07:01

Electrophoretic Delivery of γ-aminobutyric Acid GABA into Epileptic Focus Prevents Seizures in Mice

Published on: May 16, 2019

8.9K

Related Experiment Videos

Last Updated: May 14, 2025

Manipulation of Epileptiform Electrocorticograms ECoGs and Sleep in Rats and Mice by Acupuncture
09:06

Manipulation of Epileptiform Electrocorticograms ECoGs and Sleep in Rats and Mice by Acupuncture

Published on: December 22, 2016

9.5K
Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
09:57

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

2.5K
Electrophoretic Delivery of γ-aminobutyric Acid GABA into Epileptic Focus Prevents Seizures in Mice
07:01

Electrophoretic Delivery of γ-aminobutyric Acid GABA into Epileptic Focus Prevents Seizures in Mice

Published on: May 16, 2019

8.9K

Area of Science:

  • Neurology
  • Global Health
  • Public Health

Background:

  • Epilepsy impacts 50 million globally, with 80% in low- and middle-income countries.
  • Asia, with over 4 billion people, has approximately 23 million individuals with epilepsy.
  • Resource limitations pose significant challenges to epilepsy management in Asia.

Purpose of the Study:

  • To review the difficulties in managing epilepsy in Asia.
  • To highlight the impact of limited resources on epilepsy care access and outcomes.
  • To identify factors influencing epilepsy management in the Asian context.

Main Methods:

  • This review synthesizes existing literature on epilepsy management in resource-constrained settings, focusing on Asia.
  • Analysis of challenges including medical expenses, treatment access, mortality, and care transitions.
  • Examination of research data availability and its impact on progress assessment.

Main Results:

  • Limited resources prevent up to 90% of epilepsy patients from receiving adequate care, despite advanced treatments in some areas.
  • Key challenges include high medical costs, restricted access to treatment, premature mortality, and difficulties in transitioning care.
  • Insufficient epilepsy research in many Asian countries hinders accurate data collection and progress monitoring.

Conclusions:

  • Addressing the significant treatment gap for epilepsy in Asia requires overcoming resource limitations.
  • Increased research, adoption of international best practices, and enhanced funding are vital for improving epilepsy care.
  • Collaborative efforts are needed to ensure better epilepsy management and outcomes in Asian communities.