Peripheral Nerve Schwannoma With Intense 68 Ga PSMA Uptake

Prostate-specific membrane antigen (PSMA) is a specific marker of the prostate cell lineage. 68 Ga-PSMA PET/CT is a sensitive and valuable imaging modality used for staging at diagnosis and restaging in cases of recurrence during the follow-up of prostate carcinoma patients. However, increased PSMA uptake can be observed in various malignancies, such as cholangiocarcinoma, hepatocellular carcinoma, adenoid cystic carcinoma, renal cell carcinoma, and in several benign conditions, such as angiolipoma. Here, we present a case of a newly diagnosed prostate carcinoma patient with a schwannoma exhibiting intense 68 Ga PSMA uptake mimicking paravertebral soft tissue metastasis of prostate cancer.