Four Faces of Infective Endocarditis: Where Thinking Outside the Box Was Crucial

Background/Objectives: Infective Endocarditis (IE) presents both a challenging diagnostic and treatment task. Methods: The incidence of IE has grown with the advancement in treatment technologies offered to patients, including intra-cardiac electrical device insertion and a variety of transcutaneous structural interventions. Results: Guidelines recommend the involvement of a multi-disciplinary approach to prompt diagnosis and decisions regarding treatment. Conclusions: We present the management conundrums of four complex cases of IE and highlight the importance of the Extended Endocarditis Team.