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Related Concept Videos

Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...

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Echocardiographer-Led Combined Transjugular Intracardiac Echocardiography and Transesophageal Echocardiography for Tricuspid Transcatheter Edge-to-Edge Repair.

JACC. Case reports·2026
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Standardized endpoint definitions for trials of transcatheter left atrial appendage closure: a consensus from the Left Atrial Appendage Academic Research Consortium†.

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Valvular Shock in the Cardiac Intensive Care Unit: Perioperative Care for Transcatheter Valve Interventions.

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Related Experiment Video

Updated: May 12, 2026

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
23:33

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Concomitant Transcatheter Edge-to-Edge Repair and Left Atrial Appendage Occlusion.

Graeme Prosperi-Porta1, Adam Dryden2, Donna Nicholson2

  • 1Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON K1Y 4W7, Canada.

Journal of Clinical Medicine
|April 12, 2025
PubMed
Summary

Concomitant mitral valve transcatheter edge-to-edge repair (M-TEER) and left atrial appendage occlusion (LAAO) are feasible procedures. This study found no major complications, suggesting potential for combined use in atrial fibrillation patients.

Keywords:
atrial fibrillationleft atrial appendage occlusionmitral regurgitationtranscatheter edge-to-edge repair

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Area of Science:

  • Interventional Cardiology
  • Structural Heart Disease
  • Cardiac Electrophysiology

Background:

  • Atrial fibrillation is common in patients undergoing mitral valve transcatheter edge-to-edge repair (M-TEER).
  • Left atrial appendage occlusion (LAAO) reduces stroke risk in atrial fibrillation.
  • Both procedures share access and imaging requirements, but combined safety data is limited.

Purpose of the Study:

  • To evaluate the safety and feasibility of performing M-TEER and LAAO concomitantly.
  • To assess procedural outcomes and complications of combined M-TEER and LAAO.

Main Methods:

  • Retrospective review of 15 patients undergoing concomitant M-TEER and LAAO from May 2019 to September 2024.
  • Analysis of procedural time, complications, and post-procedural device performance via transesophageal echocardiography.

Main Results:

  • Successful LAAO in all 15 patients with an additional 15 minutes of procedural time.
  • No deaths or major vascular complications occurred.
  • No device-related thrombus or significant peri-device leak observed on follow-up echocardiography.

Conclusions:

  • Concomitant M-TEER and LAAO is a feasible approach.
  • Further prospective studies and randomized trials are warranted to confirm clinical benefits.