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Updated: May 14, 2025

Novel Sequence Discovery by Subtractive Genomics
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Novel Sequence Discovery by Subtractive Genomics

Published on: January 25, 2019

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Emergence of Novel Anaplasma Species in the Mediterranean Area

Valentina Chisu1, Rosanna Zobba2, Giovanna Masala1

  • 1Istituto Zooprofilattico Sperimentale "G. Pegreffi" della Sardegna, Via Duca degli Abruzzi 8, 07100 Sassari, Italy.

Animals : an Open Access Journal From MDPI
|April 12, 2025
PubMed

Insights

New Anaplasma strains, including Candidatus Anaplasma cinensis and Anaplasma phagocytophilum-like 2, have emerged in Sardinian livestock. This highlights the need for enhanced surveillance and diagnostics for tick-borne pathogens in the Mediterranean region.

Area of Science:

  • Veterinary Medicine
  • Molecular Biology
  • Public Health

Background:

  • Emerging Anaplasma strains in the Mediterranean present diagnostic and treatment challenges.
  • Anaplasma platys and Anaplasma phagocytophilum are significant tick-borne pathogens.
  • Limited data exists on Anaplasma species in Sardinian livestock.

Purpose of the Study:

  • To identify Anaplasma species genetically related to zoonotic agents in Sardinian horses, cattle, and swine.
  • To investigate the presence of Anaplasma species, including those related to A. phagocytophilum and A. platys.

Main Methods:

  • Molecular approaches were utilized.
  • Specific genes were targeted for detection.

Main Results:

  • Confirmed the presence of Candidatus Anaplasma turritanum.
  • Revealed the emergence of Candidatus Anaplasma cinensis.
  • Identified an Anaplasma phagocytophilum-like strain (A. phagocytophilum-like 2) in Sardinian horses and cattle.

Conclusions:

  • Findings underscore the importance of ongoing surveillance in Sardinia and Mediterranean regions.
  • There is an urgent need for enhanced diagnostic tools and preventive strategies.
  • Increased vigilance is crucial for both veterinary and human health due to the zoonotic potential of emerging strains.
Keywords:
Candidatus Anaplasma boleenseCandidatus Anaplasma cinensisemerging infectious diseasesreservoirs of infectionzoonosis

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