A Novel Fiber-Optical Fabry-Perot Microtip Sensor for 2-Propanol

Area of Science:

• Biomedical Engineering
• Chemical Sensing
• Optical Physics

Background:

• 2-Propanol is a volatile organic compound found in exhaled breath.
• Elevated levels of 2-propanol can indicate certain diseases.
• Accurate detection of 2-propanol is crucial for early disease diagnosis.

Purpose of the Study:

• To develop a novel fiber-optic sensor for detecting 2-propanol.
• To investigate the sensitivity and stability of the developed sensor.
• To explore the potential of this sensor for non-invasive disease diagnosis.

Main Methods:

• Fabrication of a microtip structure optical fiber sensor using light-guided induced polymerization.
• Characterization of the sensor's response to varying concentrations of 2-propanol.
• Evaluation of sensor stability and resolution.

Main Results:

• The optimized optical fiber sensor (OFS) measured approximately 15 µm.
• The OFS demonstrated high sensitivity to 2-propanol (-71.1 ± 2.1 pm/ppm).
• The sensor exhibited good stability (standard deviation of 0.15 nm) and a resolution of 3.18 ppm.

Conclusions:

• The developed fiber-optic Fabry-Perot interferometric sensor is effective for 2-propanol detection.
• The sensor's sensitivity, stability, and ease of fabrication make it suitable for biomedical applications.
• This technology holds potential for non-invasive disease detection through biomarker analysis.