Related Experiment Video
Updated: May 14, 2025

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
Pharmacologic Management of Non-Traumatic Dental Conditions in US Emergency Departments, 2018-2022
Leah I Leinbach1, Xiaobai Li2, Timothy Iafolla1
1National Institute of Dental & Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA.
Objective:
This study examines opioid and antibiotic prescribing by United States emergency departments (EDs) for non-traumatic dental conditions (NTDCs) between 2018 and 2022.
Methods:
This is a secondary analysis of nationally representative ED visits using the National Hospital Ambulatory Medical Care Survey (NHAMCS) with an NTDC as the primary discharge diagnosis. Descriptive statistics and odds ratios using chi-squared testing and multivariable logistic regression were used to examine analgesic and antibiotic prescriptions, as well as patient, visit, and hospital characteristics.
Results:
There were 1,838,729 weighted ED visits for NTDCs between 2018 and 2022, 1.3% of all visits. Findings demonstrate a continued decline in NTDC visits resulting in an opioid, with an increase in those with non-opioids. Overall, 25% of NTDC visits included an opioid analgesic in 2022, compared to 33% in 2018. The proportion of visits with non-opioid analgesics increased over the study period; nearly 60% of NTDCs seen in 2020 included a non-opioid analgesic. Overall, 63% included an antibiotic, with the highest proportion observed in 2020 (70%). No increase in the proportion of ED visits for NTDCs was seen between the pandemic years (2020-2022) and the pre-pandemic period (2018-2019).
Conclusions:
Antibiotics and non-opioid analgesics were a common approach used by ED providers during the pandemic years. Opioid prescriptions for NTDCs declined between 2018 and 2022, while antibiotic prescriptions remained roughly stable. Reducing avoidable opioid and antibiotic prescriptions, and more broadly ED visits for NTDCs, requires a comprehensive approach.
Related Concept Videos
Drug Delivery: Enteral Route
Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Peptic Ulcer Disease IV: Management
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
Adrenergic Agonists: Therapeutic Uses
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and...
Tonsillitis II: Management

