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Published on: May 19, 2022
Outcomes of High Risk and Complicated Type B Aortic Dissections Treated with Thoracic Endovascular Aortic Repair
Amanda C Filiberto1, Zdenek Novak1, Ali Azizzadeh2
1Division of Vascular Surgery and Endovascular Therapy, University of Alabama, Birmingham, AL, USA.
Objective:
The Society for Vascular Surgery (SVS) and the Society for Thoracic Surgery published reporting standards defining complicated and uncomplicated type B aortic dissections (TBADs) and included previously undefined high risk features. This retrospective review of multi-institution SVS Vascular Quality Initiative (VQI) post-approval study (VQI PAS) data aimed to evaluate the outcomes of patients with high risk TBAD (hrTBAD) and complicated TBAD (cTBAD) treated with thoracic endovascular aortic repair (TEVAR).
Methods:
The data of 641 patients collected from 2013 to 2023 were included. Patients were stratified by aortic dissection acuity: 191 complicated (cTBAD; defined as those with rupture or malperfusion) and 450 high risk (hrTBAD; defined as having refractory pain, refractory hypertension, or aortic diameter ≥ 40 mm). Uni- and multivariable analyses were used to determine the differences in outcomes by aortic dissection acuity for post-operative death, complications, and re-intervention.
Results:
Demographics and comorbidities were similar between the groups. A higher proportion of patients within the cTBAD group were transferred from an outside facility and had a pre-operative creatinine ≥ 1.8 mg/dL. Post-operative complications were more common in the cTBAD group. On Kaplan-Meier analysis, there was a lower 30 day, one year, and five year survival after TEVAR in the cTBAD group, but without differences in re-intervention.
Conclusion:
Patients with cTBAD undergoing TEVAR have poorer peri-operative and long term outcomes compared with those with hrTBAD. More studies are necessary to better elucidate the implications and long term benefits of TEVAR for patients with hrTBAD.
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