Related Experiment Video
Updated: Jun 21, 2026
Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
Published on: February 12, 2022
Ten years of robot-assisted versus laparoscopic total mesorectal excision for rectal cancer (short-term RESOLUTION)
Rauand Duhoky1,2, Ritch T J Geitenbeek3,4, Guglielmo Niccolò Piozzi1
1Department of Colorectal Surgery, Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom.
Background:
Total mesorectal excision is the gold standard for rectal cancer surgery, with laparoscopic and robot-assisted approaches commonly employed. While robot-assisted surgery may offer technical advantages, there is limited evidence comparing short-term outcomes of laparoscopic and robot-assisted techniques, particularly in Western European populations. This study aimed to assess the short-term outcomes of laparoscopic vs robot-assisted total mesorectal excision for rectal cancer.
Methods:
This multicenter, international, retrospective cohort study included 1749 patients who underwent laparoscopic or robot-assisted total mesorectal excision from January 2014 to January 2024. Inverse probability of treatment weighting was applied to minimize confounding. Primary outcomes were length of stay, operative time, and conversion rates. Secondary outcomes included complications and pathological outcomes within 90 days, and readmissions and reinterventions within 30 days.
Results:
The final cohort included 680.9 laparoscopic and 1057.5 robot-assisted cases after weighting. Robot-assisted surgery showed lower conversion rates (6.1% vs 3.5%, P = .025), higher rates of primary anastomosis (80.1% vs 92.1%, P < .001), and fewer stoma formations (78.4% vs 63.7%, P < .001). Pathological outcomes indicated a higher rate of complete mesorectal excision in the robot-assisted group (77.2% vs 86.0%, P < .001), though these data were not available for all centers. Operative time was longer in the robot-assisted cohort (181.0 vs 220.0 minutes, P < .001), but no significant differences were observed in postoperative complications, length of stay, anastomotic leakage, or 30-day reintervention rates.
Conclusion:
Robot-assisted surgery low anterior resection demonstrated improved short-term outcomes with lower conversion rates, higher rates of complete mesorectal excision, and higher restorative procedure rates, which may influence longer term oncological and patient quality of life outcomes.
Trial Registration:
https://www.isrctn.com/ISRCTN75281193.
