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Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
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Related Experiment Video

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A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay
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Octopamine alters yellow mealworm body composition.

V Hill1, L Williams1, A Salter1

  • 1School of Biosciences, University of Nottingham, Loughborough LE12 5RD, UK.

Animal : an International Journal of Animal Bioscience
|April 13, 2025
PubMed
Summary
This summary is machine-generated.

Octopamine (OA) supplementation in yellow mealworms significantly increased protein content and decreased fat. This manipulation of insect nutrient composition shows potential for creating higher-value sustainable protein feed ingredients.

Keywords:
DepositionInsectsMonoamineNutrientsRepartitioning

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Area of Science:

  • Insect nutrition and sustainable protein production
  • Comparative endocrinology of invertebrates and vertebrates
  • Biotechnology for enhanced feed ingredients

Background:

  • The insect industry is emerging as a source of sustainable protein.
  • Octopamine (OA), a monoamine in invertebrates, is functionally similar to noradrenaline in mammals.
  • Beta-2 adrenergic agonists in mammals improve body composition by increasing protein and decreasing fat.

Purpose of the Study:

  • To investigate the effects of octopamine (OA) on the growth and body composition of Tenebrio molitor larvae.
  • To determine if OA can induce favorable changes in insect body composition, similar to beta-2 adrenergic agonists in mammals.
  • To assess the potential of OA as a tool for enhancing the nutritional value of mealworms for feed.

Main Methods:

  • Tenebrio molitor larvae were fed a diet containing octopamine (OA) at 5 μg/g or a control diet for 35 days.
  • Larval weight, group weight, and cumulative pupation rates were monitored throughout the feeding period.
  • Proximate nutrient composition (fat, crude protein) and fatty acid profiles of the mealworms were analyzed at the end of the study.

Main Results:

  • Octopamine (OA) supplementation showed trends towards increased larval and group weight after 18 days and delayed pupation.
  • After 35 days, OA treatment significantly decreased fat content by 8% and increased crude protein (CP) by 6% in mealworm dry matter.
  • OA had minimal impact on fatty acid composition, with slight reductions in palmitoleic and oleic acids.

Conclusions:

  • Octopamine (OA) treatment effectively manipulated mealworm body composition, increasing protein and reducing fat content.
  • These findings demonstrate the potential to enhance the nutritional profile of mealworms, making them a more valuable feed ingredient.
  • OA supplementation offers a promising strategy for improving the sustainability and quality of insect-based protein production.