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Updated: May 13, 2025

Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm
Published on: May 4, 2020
Effects of stress on cognitive performance
1Department of Chemical Sciences (Biochemistry Unit), Faculty of Science, Kings University, Odeomu, Osun State, Nigeria.
Abstract:
Stress remains a pervasive challenge in modern life, exerting significant impacts on cognitive performance and overall well-being by triggering release of stress hormones like adrenaline and cortisol. It has profound implications for education, work performance, and everyday life, impacting cognitive performance, health outcomes, and social relationships. It does this by impacting memory, attention and focus, informed decision-making, developmental and cognitive performance, work and educational performance, genetic and epigenetic influence, and public health. When a stressor is perceived, the hypothalamus in the brain signals the pituitary gland to release adrenocorticotropic hormone, hence adrenaline is quickly released into the bloodstream, causing immediate physiological changes and thus releasing cortisol gradually to help maintain the body's response to stress over a longer period through the hypothalamic-pituitary-adrenal and sympathetic-adrenomedullar axis. The impacts can be short-term or long-term focusing on the working memory, pre-frontal cortex, amygdala, and hippocampus. By recognizing these implications and implementing targeted interventions, we can foster environments that support resilience, optimize performance, and enhance overall well-being across diverse contexts. This chapter also highlighted some mitigation strategies to reduce stress-related activities and improve cognitive performance, such as cognitive-behavioral therapy, mindfulness-based stress reduction, healthy lifestyle adoption, pet therapy, time management and prioritization, and workplace interventions.
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