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Drug Dosing: Geriatric Patients

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...

Pharmacodynamics in Geriatric Patients: Effects of Age

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

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Related Experiment Video

Updated: Jul 3, 2026

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Published on: January 24, 2020

Experiences With an Intervention Based on Geriatric Assessment With Management: A Qualitative Study.

May Ingvild Volungholen Sollid^1,2, Line Melby^2,3, Marit Slaaen^1,4

¹Research Centre for Age Related Functional Decline and Diseases, Innlandet Hospital Trust, Ottestad, Norway.

|April 14, 2025

Summary

Older cancer patients and nurses valued a systematic, patient-centered approach with regular contact from a geriatric assessment intervention. This improved care experiences for elderly individuals with cancer.

Keywords:

cancer nursing care coordination geriatric assessment older adults patient‐centered care radiotherapy thematic analysis

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Area of Science:

Geriatric oncology
Qualitative research
Healthcare interventions

Background:

Geriatric assessment with management (GAM) is an intervention for older patients with cancer.
Understanding patient and nurse experiences is crucial for successful implementation.

Purpose of the Study:

To explore older patients' experiences with a GAM intervention.
To understand cancer nurses' experiences implementing GAM and their perspectives.

Main Methods:

Qualitative descriptive interview study adhering to COREQ guidelines.
Individual interviews with 8 older patients (mean age 75) and 11 cancer nurses.
Inductive thematic analysis of collected data.

Main Results:

Three primary themes emerged: Systematic approach, Patient-centeredness, and Regular and professional contact.
These themes highlight key aspects of the intervention valued by participants.
The findings indicate positive reception of the GAM intervention.

Conclusions:

The GAM intervention was perceived positively by older cancer patients and nurses.
A systematic, patient-centered approach with consistent professional contact is vital for effective geriatric oncology care.
Further research can build upon these findings to optimize interventions for this population.