A scientometric study on research trends and characteristics of ameloblastoma

Ameloblastoma is a benign tumor derived from odontogenic epithelium in the jaws. The purpose of this study was to analyze the scientometric characteristics and research trends of ameloblastoma.

All the papers on ameloblastoma were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2014 and 2014-2024 in the analysis of research trends.

There were 2507 papers on ameloblastoma, with total citations of 34,691 and the h index of 70. The related disorders of the diagnosis of ameloblastoma were mandibular neoplasms, maxillary neoplasms, ameloblastic carcinoma, odontogenic cyst, lung neoplasms, and teratoma. Before 2014, bone graft/transplantation, osteotomy, reconstructive surgical procedures, surgical flaps, cell differentiation, and cytology were more frequent keywords. After 2014, biology research on BRAF protein, gene mutation, cytokeratin 19, biomarkers, epithelial mesenchymal transition, signal transduction, tumor microenvironment, and carcinogenesis were more frequent keywords. Clinical studies on cohort analysis, cone beam computed tomography, quality of life, fine needle aspiration biopsy, incisional biopsy, surgical margin, and hemi-mandibulectomy were more common. Experiment methods such as dog, tumor cell line, cell migration, gene expression, real time polymerase chain reaction, and western blotting were also more frequent keywords after 2014.

This scientometric study elucidated the current scenario and research trends of ameloblastoma, and would help in improving in reciprocal collaboration and communication for investigations on this tumor.