Heterotopic cervical pregnancy: Case report and literature review

Heterotopic cervical ectopic pregnancy (CEP) is a rare form of ectopic pregnancy, that involves implantation of gestational sac in both the cervical canal and uterine cavity. This condition poses high risks of severe complications like lethal vaginal bleeding and abortion. Transvaginal ultrasonography is the primary diagnostic tool. Risk factors may vary from prior cesarean delivery to the utilization of Assisted Reproductive Technologies (ART). Despite the research conducted on this condition, the best treatment strategy has not been established. This study discusses a rare case of cervical heterotopic pregnancy, emphasizing early diagnosis. Our case underwent in-vitro fertilization (IVF). We used potassium chloride (KCL) and methotrexate (MTX) as treatment. At first, the cervical gestational sac was expelled but unfortunately, later, the intrauterine gestational sac was also aborted. We also reviewed 25 cases (1980-2024) which demonstrated the importance of early diagnosis of heterotopic cervical pregnancy and that most cases are likely to have positive outcomes.