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Updated: May 13, 2025
06:38
Isolation of Adult Spinal Cord Nuclei for Massively Parallel Single-nucleus RNA Sequencing
Published on: October 12, 2018
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The China National GeneBank Sequence Archive (CNSA) 2024 update
Weiwen Wang1,2,3, Cong Tan4,5, Ling Li1,2,3
1Guangdong Provincial Genomics Data Center, BGI Research, Beishan Road, Yantian District, Shenzhen 518120, China.
Horticulture Research
|April 14, 2025
Summary
The China National GeneBank Sequence Archive (CNSA) offers open access to multiomics data, addressing challenges in managing vast sequencing information. CNSA supports global research and biodiversity preservation with enhanced features and services.
Area of Science:
- Genomics and Bioinformatics
- Data Science in Life Sciences
Background:
- Sequencing technology advancements create massive datasets, posing data management and reusability challenges.
- The China National GeneBank Sequence Archive (CNSA) was established in 2017 to address these challenges in multiomics data archiving.
- New technologies like spatial transcriptome sequencing require advanced data archiving solutions.
Purpose of the Study:
- To present state-of-the-art enhancements and new features of the CNSA.
- To highlight CNSA's role in archiving, sharing, and reusing multiomics data.
- To showcase CNSA's support for global cooperation in biodiversity preservation.
Main Methods:
- CNSA provides public archiving and open-sharing services for diverse sequencing data and metadata.
- Data types include genome, transcriptome, metabolism, and proteome from various biological levels.
- Services cover data curation, preservation, and open-sharing for publications.
Main Results:
- As of 2024, CNSA has archived over 16.3 petabytes of data.
- CNSA has supported over 1581 publications from more than 560 institutions.
- CNSA plays a key role in global projects like the 10,000 Plant Genomes Project.
Conclusions:
- CNSA is a critical infrastructure for multiomics data management and reusability.
- The repository's continuous enhancements support the global research community.
- CNSA is recommended by major academic publishers, underscoring its importance.
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