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Updated: Aug 19, 2026

Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs
Published on: July 23, 2016
Distribution of 110Ag-silver nitrate prophylaxis solutions following eyedrop application to the albino rabbit
The distribution of radioactive silver-110 labelled silver nitrate in the eye of the albino rabbit was determined by eyedrop application of 1, 2 and 6% solutions. The distribution of the radiotracer was determined at 1 h and 1 day post-application. Localization at 1 h was primarily in the cornea and conjunctiva. Washout of this radiotracer was rapid.
The distribution of radioactive silver-110 labelled silver nitrate in the eye of the albino rabbit was determined by eyedrop application of 1, 2 and 6% solutions. The distribution of the radiotracer was determined at 1 h and 1 day post-application. Localization at 1 h was primarily in the cornea and conjunctiva. Washout of this radiotracer was rapid.
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